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產品規格
售價
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BN41880R-50ul
50ul
￥1486.00
交叉反應：Human,Mouse,Rat(predicted:Dog,Cow,Horse,Rabbit,Sheep) 推薦應用：WB,IHC-P,IHC-F,IF,ELISA
BN41880R-100ul
100ul
￥2360.00
交叉反應：Human,Mouse,Rat(predicted:Dog,Cow,Horse,Rabbit,Sheep) 推薦應用：WB,IHC-P,IHC-F,IF,ELISA
BN41880R-200ul
200ul
￥3490.00
交叉反應：Human,Mouse,Rat(predicted:Dog,Cow,Horse,Rabbit,Sheep) 推薦應用：WB,IHC-P,IHC-F,IF,ELISA
產品描述
| 英文名稱 | Amphiregulin |
| 中文名稱 | 雙調蛋白/結腸直腸細胞源性生長因子抗體 |
| 別 名 | AR; Colorectum cell derived growth factor; CRDGF; A REG; AR antibody; AREG; Colorectum cell derived growth factor; CRDGF; MGC13647; Schwannoma derived growth factor; SDGF; AREG_HUMAN. |
| 研究領域 | 腫瘤 細胞生物 免疫學 神經生物學 生長因子和激素 轉錄調節因子 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應 | Human, Mouse, Rat, (predicted: Dog, Cow, Horse, Rabbit, Sheep, ) |
| 產品應用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:ug/test IF=1:100-500 （石蠟切片需做抗原修復） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 16kDa |
| 細胞定位 | 細胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Amphiregulin:185-252/252 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 產品介紹 | Amphiregulin expression is induced by phorbol ester, estrogen, androgen, and other EGFR ligands. In vitro, amphiregulin functions as an autocrine growth stimulator to drive proliferation of colon carcinoma cells, normal and oncogene-transformed mammary epithelial cells, cervical carcinoma cells, prostate cancer cells, and keratinocytes. Amphiregulin is important in the development of human placenta and murine mammary gland. It is reportedly overexpressed in human cancers of breast, colon, stomach and pancreas. Function: Ligand of the EGF receptor/EGFR. Autocrine growth factor as well as a mitogen for a broad range of target cells including astrocytes, Schwann cells and fibroblasts. Subunit: The immature precursor interacts with CNIH. Subcellular Location: Membrane; Single-pass membrane protein. Similarity: Belongs to the amphiregulin family. Contains 1 EGF-like domain. SWISS: P15514 Gene ID: 374 Database links: Entrez Gene: 374 Human Entrez Gene: 727738 Human Entrez Gene: 11839 Mouse Omim: 104640 Human SwissProt: P15514 Human SwissProt: P31955 Mouse Unigene: 270833Human Unigene: 645475 Human Unigene: 8039 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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